Article
Molecular characterization of KIR3DL3.
Immunogenetics - 1 Jan 2006
Trundley Anita E, Hiby Susan E, Chang Chiwen, Sharkey Andrew M, Santourlidis Simeon, Uhrberg Markus, Trowsdale John, Moffett Ashley
Abstract excerpt
Killer-cell immunoglobulin-like receptors (KIRs) are a structurally and functionally diverse family of molecules expressed by natural killer (NK) cells and T-cell subsets. The most centromeric gene in the human KIR cluster is KIR3DL3, a framework gene that is present in all haplotypes. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
