Article
A functional variant at miR-132-3p, miR-212-3p, and miR-361-5p binding site in CD80 gene alters susceptibility to gastric cancer in a Chinese Han population.
Medical oncology (Northwood, London, England) - 1 Aug 2014
Wu Ruirong, Li Fuchao, Zhu Jianjie, Tang Rong, Qi Qinghua, Zhou Xinru, Li Rui, Wang Weipeng, Hua Dong, Chen Weichang
Abstract excerpt
A number of single-nucleotide polymorphisms within the 3'-UTR of genes have been shown to relate to the occurrence of cancers. In this study, by using polymerase chain reaction-restriction fragment length analysis method, we determined an SNP rs1599795 in the 3'-UTR of CD80 gene in 183 gastric cancer patients and 348 healthy controls. Statistical analysis results showed that SNP rs1599795 genotypes were...
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