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Article

USP33, a new player in lung cancer, mediates Slit-Robo signaling

1 Jul 2014

Abstract excerpt

Ubiquitin specific protease 33 (USP33) is a multifunctional protein regulating diverse cellular processes. The expression and role of USP33 in lung cancer remain unexplored. In this study, we show that USP33 is down-regulated in multiple cohorts of lung cancer patients and that low expression of USP33 is associated with poor prognosis. USP33 mediates Slit-Robo signaling in lung cancer cell migration....

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PMID: 24981056
DOI: 10.1007/s13238-014-0070-z

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