Identification of a melanoma susceptibility locus and somatic mutation in TET2.

doi:10.1093/carcin/bgu140

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Identification of a melanoma susceptibility locus and somatic mutation in TET2.

Carcinogenesis - 1 Sept 2014

Song Fengju, Amos Christopher I, Lee Jeffrey E, Lian Christine G, Fang Shenying, Liu Hongliang, MacGregor Stuart, Iles Mark M, Law Matthew H, Lindeman Neal I, Montgomery Grant W, Duffy David L, Cust Anne E, Jenkins Mark A, Whiteman David C, Kefford Richard F, Giles Graham G, Armstrong Bruce K, Aitken Joanne F, Hopper John L, Brown Kevin M, Martin Nicholas G, Mann Graham J, Bishop D Timothy, Bishop Julia A Newton, Kraft Peter, Qureshi Abrar A, Kanetsky Peter A, Hayward Nicholas K, Hunter David J, Wei Qingyi, Han Jiali

Abstract excerpt

Although genetic studies have reported a number of loci associated with melanoma risk, the complex genetic architecture of the disease is not yet fully understood. We sought to identify common genetic variants associated with melanoma risk in a genome-wide association study (GWAS) of 2298 cases a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dioxygenases

Share to DNA-Binding Proteins

Share to Genome-Wide Association Study

Share to Melanoma

Share to Proto-Oncogene Proteins

Share to Risk Factors

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 24980573
DOI: 10.1093/carcin/bgu140
PMCID: PMC4146422

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24980573-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a melanoma susceptibility locus and somatic mutation in TET2.PMID 24980573Read ↗

Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.Semantic proximity Read ↗

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.Semantic proximity Read ↗

Integrated case-control and somatic-germline interaction analyses of melanoma susceptibility genes.Semantic proximity Read ↗

A Systematic Review of Cancer Risks Associated With Mitf VariantsSemantic proximity Read ↗

Whole-exome sequencing of oral mucosal melanoma reveals mutational profile and therapeutic targets.Semantic proximity Read ↗

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.Semantic proximity Read ↗

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.Semantic proximity Read ↗

Genome-wide association study identifies three new melanoma susceptibility loci.Semantic proximity Read ↗

DNA methylation/hydroxymethylation in melanomaSemantic proximity Read ↗

A high-penetrance intergenic variant at 9p21 confers melanoma susceptibilitySemantic proximity Read ↗

Genetic variation at KIT locus may predispose to melanoma.Semantic proximity Read ↗

Cancer risks associated with the germline MITF(E318K) variant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.