Article
Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample.
Archives of general psychiatry - 1 May 2007
Laucht Manfred, Skowronek Markus H, Becker Katja, Schmidt Martin H, Esser Günter, Schulze Thomas G, Rietschel Marcella
Abstract excerpt
CONTEXT: Recent evidence suggests that gene x environment interactions could explain the inconsistent findings of association studies relating the dopamine transporter (DAT1) gene with attention-deficit/hyperactivity disorder (ADHD). OBJECTIVE: To examine whether psychosocial adversity moderated the effect of genetic variation in DAT1 on ADHD symptoms in adolescents from a high-risk community sample. DESIGN:...
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