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Article

The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2014

Reichel Martin, Richter-Schmidinger Tanja, Mühle Christiane, Rhein Cosima, Alexopoulos Panagiotis, Schwab Sibylle G, Gulbins Erich, Kornhuber Johannes

Abstract excerpt

BACKGROUND: Acid sphingomyelinase (ASM) is a key regulator of ceramide-dependent signalling pathways. Among others, activation of ASM can be induced by CD95 or cytokine signalling and by cellular stress resulting from inflammation or infection. Increased ASM activity was observed in a variety of...

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Identifiers

PMID: 24977483
DOI: 10.1159/000362986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24977483-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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