Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Murine abdominal aortic aneurysm model by orthotopic allograft transplantation of elastase-treated abdominal aorta.

Journal of vascular surgery - 1 Dec 2015

Liu Zhenjie, Wang Qiwei, Ren Jun, Assa Carmel Rebecca, Morgan Stephanie, Giles Jasmine, Han Qi, Liu Bo

Abstract excerpt

OBJECTIVE: Murine models have proved instrumental in studying various aspects of abdominal aortic aneurysm (AAA), from identification of underlying pathophysiologic changes to the development of novel therapeutic strategies. In the current study, we describe a new model in which an elastase-treated donor aorta is transplanted to a recipient mouse and allowed to progress to aneurysm. We hypothesized that by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allografts
Share to Aorta, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aortic Aneurysm, Abdominal

Share to Cellular Microenvironment

Share to Mice, Inbred C57BL

Share to Mice, Transgenic

Share to Muscle, Smooth, Vascular

Share to Pancreatic Elastase

Source

Open in PubMed Open full text

Identifiers

PMID: 24974783
DOI: 10.1016/j.jvs.2014.05.019
PMCID: PMC4277509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Murine abdominal aortic aneurysm model by orthotopic allograft transplantation of elastase-treated abdominal aorta.PMID 24974783Read ↗

Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds.Semantic proximity Read ↗

Extra- and Intraluminal Elastase Induce Morphologically Distinct Abdominal Aortic Aneurysms in Mice and Thus Represent Specific Subtypes of Human Disease.Semantic proximity Read ↗

Differential gender- and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms.Semantic proximity Read ↗

Inhibition or deletion of angiotensin II type 1 receptor suppresses elastase-induced experimental abdominal aortic aneurysms.Semantic proximity Read ↗

Mouse models of abdominal aortic aneurysms.Semantic proximity Read ↗

Elastogenic inductability of smooth muscle cells from a rat model of late stage abdominal aortic aneurysms.Semantic proximity Read ↗

Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysmSemantic proximity Read ↗

Loss of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosisSemantic proximity Read ↗

Adenosine 2A receptor modulates inflammation and phenotype in experimental abdominal aortic aneurysms.Semantic proximity Read ↗

Animal models in the research of abdominal aortic aneurysms development.Semantic proximity Read ↗

Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion.Semantic proximity Read ↗

Spatiotemporal mapping of matrix remodelling and evidence of in situ elastogenesis in experimental abdominal aortic aneurysms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.