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Article

ETS1–HMGA2 Axis Promotes Human Limbal Epithelial Stem Cell Proliferation

18 Jan 2023

Abstract excerpt

Purpose: This study aimed to investigate the role and molecular mechanism of ETS1 in the proliferation and differentiation of human limbal epithelial stem cells (LESCs). Methods: RNA-seq and quantitative real-time PCR were used to determine gene expression changes when ETS1 and HMGA2 was knocked down using short-hairpin RNAs or overexpressed by lentivirus. Immunofluorescence and flow cytometry experiments were...

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PMID: 36652264
DOI: 10.1167/iovs.64.1.12

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