Article
The effect of hyaluronan-based delivery of stromal cell-derived factor-1 on the recruitment of MSCs in degenerating intervertebral discs.
Biomaterials - 1 Sept 2014
Pereira Catarina Leite, Gonçalves Raquel M, Peroglio Marianna, Pattappa Girish, D'Este Matteo, Eglin David, Barbosa Mário A, Alini Mauro, Grad Sibylle
Abstract excerpt
Intervertebral disc (IVD) degeneration is the leading cause of low back pain and disability in the active population. Transplantation of mesenchymal stem cells (MSCs) in a hydrogel carrier can induce regenerative effects in degenerated IVDs. Moreover, it was found that degenerative discs release...
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