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Article

Single-Cell Transcriptomic Profiling and Machine Learning Integration Unveil Stromal Cell Heterogeneity in Endometriosis.

Human mutation - 1 Jan 2026

Zhang Huipeng, Luo Yuli

Abstract excerpt

Background: Endometriosis (EMs) affects approximately 10% of reproductive-age women worldwide, yet its pathogenesis remains incompletely understood. Abnormal cell differentiation and somatic mutations in the ectopic endometrial microenvironment play critical roles in disease progression and treatment response heterogeneity. This study is aimed at elucidating the molecular mechanisms underlying ectopic endometrial...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42040898
DOI: 10.1155/humu/5565366
PMCID: PMC13106875

Genes

SPP1
ESR1
HOXA10
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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