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Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress

26 Jun 2014

Abstract excerpt

Telomere shortening is observed in peripheral mononuclear cells from patients with major depressive disorder (MDD). Whether this finding and its biological causes impact the health of the brain in MDD is unknown. Brain cells have differing vulnerabilities to biological mechanisms known to play a role in accelerating telomere shortening. Here, two glia cell populations (oligodendrocytes and astrocytes) known to...

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Share to Circadian rhythm and melatonin
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24967945
DOI: 10.1017/s1461145714000698

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