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Targeting the association between telomere length and immuno-cellular bioenergetics in female patients with Major Depressive Disorder

14 Jun 2018

Abstract excerpt

Major Depressive Disorder (MDD) has been associated with telomere dysfunction and alterations in mitochondrial activity, which seem to be co-regulated in human cells. To investigate this co-regulation in MDD, we assessed telomere length (TL) in peripheral blood mononuclear cells (PBMC) and selected immune cell subsets by quantitative fluorescence in situ hybridization and mitochondrial respiratory activity in...

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PMID: 29925891
DOI: 10.1038/s41598-018-26867-7

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