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The Role of Glia Telomere Dysfunction in the Pathogenesis of Central Nervous System Diseases

19 Jan 2024

Abstract excerpt

Maintaining the telomere length is decisive for the viability and homeostasis process of all the cells of an organism, including human glial cells. Telomere shortening of microglial cells has been widely associated with the onset and progression of neurodegenerative diseases such as Parkinson's and Alzheimer's disease. Additionally, traumatic brain injury appears to have a positive correlation with the...

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Share to Epigenetics and DNA Methylation
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PMID: 38240992
DOI: 10.1007/s12035-024-03947-6

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