Article
Analysis of cross-reactive neutralizing antibodies in human HFMD serum with an EV71 pseudovirus-based assay.
PloS one - 1 Jan 2014
Zhang Huafei, An Dong, Liu Wei, Mao Qunying, Jin Jun, Xu Lin, Sun Shiyang, Jiang Liping, Li Xiaojun, Shao Jie, Ma Hongxia, Huang Xueyong, Guo Shijie, Chen Haiying, Cheng Tong, Yang Lisheng, Su Weiheng, Kong Wei, Liang Zhenglun, Jiang Chunlai
Abstract excerpt
Hand, foot and mouth disease, associated with enterovirus 71 (EV71) infections, has recently become an important public health issue throughout the world. Serum neutralizing antibodies are major indicators of EV71 infection and protective immunity. However, the potential for cross-reactivity of neutralizing antibodies for different EV71 genotypes and subgenotypes is unclear. Here we measured the cross-reactive...
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