Article
Involvement of upregulated SYF2 in Schwann cell differentiation and migration after sciatic nerve crush.
Cellular and molecular neurobiology - 1 Oct 2014
Zhou Zhengming, Liu Yang, Nie Xiaoke, Cao Jianhua, Zhu Xiaojian, Yao Li, Zhang Weidong, Yu Jiang, Wu Gang, Liu Yonghua, Yang Huiguang
Abstract excerpt
SYF2 is a putative homolog of human p29 in Saccharomyces cerevisiae. It seems to be involved in pre-mRNA splicing and cell cycle progression. Disruption of SYF2 leads to reduced α-tubulin expression and delayed nerve system development in zebrafish. Due to the potential of SYF2 in modulating microtubule dynamics in nervous system, we investigated the spatiotemporal expression of SYF2 in a rat sciatic nerve crush...
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