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Article

Detection of genomic variations and DNA polymorphisms and impact on analysis of meiotic recombination and genetic mapping.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jul 2014

Qi Ji, Chen Yamao, Copenhaver Gregory P, Ma Hong

Abstract excerpt

DNA polymorphisms are important markers in genetic analyses and are increasingly detected by using genome resequencing. However, the presence of repetitive sequences and structural variants can lead to false positives in the identification of polymorphic alleles. Here, we describe an analysis strategy that minimizes false positives in allelic detection and present analyses of recently published resequencing data...

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PMID: 24958856
DOI: 10.1073/pnas.1321897111
PMCID: PMC4103349

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