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Article

Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae.

Parasites & vectors - 23 Jun 2014

Brenton Ashley A, Souvannaseng Lattha, Cheung Kong, Anishchenko Michael, Brault Aaron C, Luckhart Shirley

Abstract excerpt

BACKGROUND: Susceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses. Despite the fact that some of these mutations are known to introduce non-synonymous substitutions in coding sequences, these mutations have largely been used to rationalize knockdown of associated target proteins to query...

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Identifiers

PMID: 24957684
DOI: 10.1186/1756-3305-7-287
PMCID: PMC4077580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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