Article
Navigating the future of bacterial molecular epidemiology.
Current opinion in microbiology - 1 Oct 2010
Baker Stephen, Hanage William P, Holt Kathryn E
Abstract excerpt
Technological advances in high-throughput genome sequencing have led to an enhanced appreciation of the genetic diversity found within populations of pathogenic bacteria. Methods based on single nucleotide polymorphisms (SNPs) and insertions or deletions (indels) build upon the framework established by multi-locus sequence typing (MLST) and permit a detailed, targeted analysis of variation within related...
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