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Article

MLST revisited: the gene-by-gene approach to bacterial genomics.

Nature reviews. Microbiology - 1 Oct 2013

Maiden Martin C J, Jansen van Rensburg Melissa J, Bray James E, Earle Sarah G, Ford Suzanne A, Jolley Keith A, McCarthy Noel D

Abstract excerpt

Multilocus sequence typing (MLST) was proposed in 1998 as a portable sequence-based method for identifying clonal relationships among bacteria. Today, in the whole-genome era of microbiology, the need for systematic, standardized descriptions of bacterial genotypic variation remains a priority. Here, to meet this need, we draw on the successes of MLST and 16S rRNA gene sequencing to propose a hierarchical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23979428
DOI: 10.1038/nrmicro3093
PMCID: PMC3980634

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