Article
Tumor initiating potential of side population cells in human gastric cancer.
International journal of oncology - 1 May 2009
Fukuda Kazumasa, Saikawa Yoshiro, Ohashi Masaki, Kumagai Koshi, Kitajima Masaki, Okano Hideyuki, Matsuzaki Yumi, Kitagawa Yuko
Abstract excerpt
Side population (SP) cells are a small subpopulation of cells with enriched source of gastric tumor-initiating cells (TICs) with stem-like cell property that are characterized by high efflux ability of Hoechst 33342 dye, reflecting high expression of several subtypes of the ATP-binding cassette transporter family that is characteristic of stem cells. The present study is the first to discover and characterize SP...
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