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Article

Circulating anti-filamin C autoantibody as a potential serum biomarker for low-grade gliomas

18 Jun 2014

Abstract excerpt

BACKGROUND: Glioma is the most common primary malignant central nervous system tumor in adult, and is usually not curable due to its invasive nature. Establishment of serum biomarkers for glioma would be beneficial both for early diagnosis and adequate therapeutic intervention. Filamins are an actin cross-linker and filamin C (FLNC), normally restricted in muscle tissues, offers many signaling molecules an...

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PMID: 24946857
DOI: 10.1186/1471-2407-14-452

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