Article
Different functions of the class I and class II chitin synthase genes, chsC and chsA, are revealed by repression of chsB expression in Aspergillus nidulans.
Current genetics - 1 Oct 2002
Ichinomiya Masayuki, Horiuchi Hiroyuki, Ohta Akinori
Abstract excerpt
The filamentous fungus, Aspergillus nidulans, genome contains at least five chitin synthase-encoding genes. chsB is essential for normal hyphal growth. chsA and chsC are likely to be cooperatively required for hyphal wall integrity. In this study, we constructed chsA chsB and chsC chsB double mutants, in which chsB expression was under a repressible promoter [ alcA(p)]. While chsA or chsC single mutants did not...
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