Article
Botrytis cinerea virulence is drastically reduced after disruption of chitin synthase class III gene (Bcchs3a).
Cellular microbiology - 1 Aug 2006
Soulié Marie-Christine, Perino Claude, Piffeteau Annie, Choquer Mathias, Malfatti Pierrette, Cimerman Agnès, Kunz Caroline, Boccara Martine, Vidal-Cros Anne
Abstract excerpt
Botrytis cinerea is an important phytopathogenic fungus requiring new methods of control. Chitin biosynthesis, which involves seven classes of chitin synthases, could be an attractive target. A fragment encoding one of the class III enzymes was used to disrupt the corresponding Bcchs3a gene in the B. cinerea genome. The resulting mutant exhibited a 39% reduction in its chitin content and an 89% reduction in its...
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