Article
Cell wall biogenesis in a double chitin synthase mutant (chsG-/chsE-) of Aspergillus fumigatus.
Fungal genetics and biology : FG & B - 1 Feb 2003
Mellado E, Dubreucq G, Mol P, Sarfati J, Paris S, Diaquin M, Holden D W, Rodriguez-Tudela J L, Latgé J P
Abstract excerpt
Previous studies (Aufauvre-Brown et al., 1997; Mellado et al., 1996a,b ) have shown that only two genes of the Aspergillus fumigatus chitin synthase family, chsG and chsE, play a role in the morphogenesis of this fungal species. An A. fumigatus strain lacking both chsG (class III CHS) and chsE (class V CHS) genes was constructed by gene replacement of the chsE gene with a copy that has its conserved coding region...
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