Article
ALK fusion and its association with other driver gene mutations in Finnish non-small cell lung cancer patients.
Genes, chromosomes & cancer - 1 Nov 2014
Tuononen Katja, Kero Mia, Mäki-Nevala Satu, Sarhadi Virinder Kaur, Tikkanen Milja, Wirtanen Tiina, Rönty Mikko, Knuuttila Aija, Knuutila Sakari
Abstract excerpt
Screening of anaplastic lymphoma tyrosine kinase (ALK) gene fusions in non-small cell lung cancer (NSCLC) patients enables the identification of the patients likely to benefit from ALK-targeted therapy. Our aim was to assess the prevalence of ALK fusion in Finnish NSCLC patients, which has not been reported earlier, and to study the presence of ALK fusion in relation to clinicopathological characteristics and...
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