Article
Tumor plasticity interferes with anti-tumor immunity.
Critical reviews in immunology - 1 Jan 2014
Chouaib Salem, Janji Bassam, Tittarelli Andres, Eggermont Alexander, Thiery Jean Paul
Abstract excerpt
Since tumor cell plasticity was first shown to be crucial in tumor promotion and immune surveillance evasion, it has become an issue of intense investigation. Several mechanisms are associated with the acquisition of tumor cell plasticity and immune evasion, including loss of epithelial phenotype through epithelial-to-mesenchymal transition (EMT). We discuss recent evidence revealing that tumor cell plasticity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.