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Alphavirus-Based Vaccines

16 Jun 2014

Abstract excerpt

Alphavirus vectors have demonstrated high levels of transient heterologous gene expression both in vitro and in vivo and, therefore, possess attractive features for vaccine development. The most commonly used delivery vectors are based on three single-stranded encapsulated alphaviruses, namely Semliki Forest virus, Sindbis virus and Venezuelan equine encephalitis virus. Alphavirus vectors have been applied as...

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PMID: 24937089
DOI: 10.3390/v6062392

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