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Article

The effect of genetic background on behavioral manifestation of Grid2(Lc) mutation.

Behavioural brain research - 1 Sept 2014

Cendelin Jan, Tuma Jan, Korelusova Ivana, Vozeh Frantisek

Abstract excerpt

Mutant mice are commonly used models of hereditary diseases. Nevertheless, these mice have phenotypic traits of the original strain, which could interfere with the manifestation of the mutation of interest. Lurcher mice represent a model of olivocerebellar degeneration, which is caused by the Grid2(Lc) mutation. Lurchers show ataxia and various cognitive and behavioral abnormalities. The most commonly used...

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Identifiers

PMID: 24937052
DOI: 10.1016/j.bbr.2014.06.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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