Article
GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence.
Diabetologia - 1 Aug 2014
Eny Karen M, Lutgers Helen L, Maynard John, Klein Barbara E K, Lee Kristine E, Atzmon Gil, Monnier Vincent M, van Vliet-Ostaptchouk Jana V, Graaff Reindert, van der Harst Pim, Snieder Harold, van der Klauw Melanie M, Sell David R, Hosseini S Mohsen, Cleary Patricia A, Braffett Barbara H, Orchard Trevor J, Lyons Timothy J, Howard Kerri, Klein Ronald, Crandall Jill P, Barzilai Nir, Milman Sofiya, Ben-Avraham Danny, Wolffenbuttel Bruce H R, Paterson Andrew D
Abstract excerpt
AIMS/HYPOTHESIS: Skin fluorescence (SF) is a non-invasive marker of AGEs and is associated with the long-term complications of diabetes. SF increases with age and is also greater among individuals with diabetes. A familial correlation of SF suggests that genetics may play a role. We therefore per...
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