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Article

New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins.

Diabetes - 1 Jul 2016

Roshandel Delnaz, Klein Ronald, Klein Barbara E K, Wolffenbuttel Bruce H R, van der Klauw Melanie M, van Vliet-Ostaptchouk Jana V, Atzmon Gil, Ben-Avraham Danny, Crandall Jill P, Barzilai Nir, Bull Shelley B, Canty Angelo J, Hosseini S Mohsen, Hiraki Linda T, Maynard John, Sell David R, Monnier Vincent M, Cleary Patricia A, Braffett Barbara H, Paterson Andrew D

Abstract excerpt

Skin fluorescence (SF) noninvasively measures advanced glycation end products (AGEs) in the skin and is a risk indicator for diabetes complications. N-acetyltransferase 2 (NAT2) is the only known locus influencing SF. We aimed to identify additional genetic loci influencing SF in type 1 diabetes (T1D) through a meta-analysis of genome-wide association studies (N = 1,359) including Diabetes Control and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27207532
DOI: 10.2337/db15-1484
PMCID: PMC4915582

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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