Article
KPNA2 predicts long term survival in patients with anaplastic oligoastrocytomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Oct 2014
Gousias Konstantinos, Niehusmann Pitt, Gielen Gerrit, Simon Matthias, Boström Jan
Abstract excerpt
The family of karyopherins comprises importins and exportins which are both involved in nucleocytoplasmic shuttling. Increased levels of karyopherin a2/importin 1 (KPNA2) and chromosome region maintenance protein 1/exportin 1 (CRM1) have been associated with poorer prognosis in patients with infi...
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