Effects of a microRNA binding site polymorphism in SLC19A1 on methotrexate concentrations in Chinese children with acute lymphoblastic leukemia.

doi:10.1007/s12032-014-0062-0

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Article

Effects of a microRNA binding site polymorphism in SLC19A1 on methotrexate concentrations in Chinese children with acute lymphoblastic leukemia.

Medical oncology (Northwood, London, England) - 1 Jul 2014

Wang Shu-mei, Sun Lu-lu, Zeng Wei-xin, Wu Wan-shui, Zhang Guo-liang

Abstract excerpt

MicroRNAs (miRNAs) are a class of short non-coding RNA that can specially bind to the 3'-untranslated region of target mRNAs and regulate gene expression at the posttranscriptional level. This study investigated the effects of a miRNA binding site polymorphism (rs1051296) in solute carrier family 19, member 1 (SLC19A1) on serum methotrexate (MTX) concentrations in Chinese children with acute lymphoblastic...

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Identifiers

PMID: 24927955
DOI: 10.1007/s12032-014-0062-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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