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Article

Combined blockade of testicular and locally made androgens in prostate cancer: a highly significant medical progress based upon intracrinology.

The Journal of steroid biochemistry and molecular biology - 1 Jan 2015

Labrie Fernand

Abstract excerpt

Recently two drugs, namely the antiandrogen MDV-3100 and the inhibitor of 17α-hydroxylase abiraterone have been accepted by the FDA for the treatment of castration-resistant prostate cancer (CRPC) with or without previous chemotherapy, with a prolongation of overall survival of 2.2-4.8 months. Wh...

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Identifiers

PMID: 24925260
DOI: 10.1016/j.jsbmb.2014.05.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24925260-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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