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Article

Impact of nonsynonymous mutations of factor X on the functions of factor X and anticoagulant activity of edoxaban.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 2015

Noguchi Kengo, Morishima Yoshiyuki, Takahashi Shinichi, Ishihara Hiroaki, Shibano Toshiro, Murata Mitsuru

Abstract excerpt

Edoxaban is an oral direct factor Xa (FXa) inhibitor and its efficacy as an oral anticoagulant is less subject to drug-food and drug-drug interaction than existing vitamin K antagonists. Although this profile of edoxaban suggests it is well suited for clinical use, it is not clear whether genetic...

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PMID: 24911450
DOI: 10.1097/MBC.0000000000000147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24911450-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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