Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery

Abstract excerpt

Hesperadin, an established human Aurora B inhibitor, was tested against cultures of <italic>Trypanosoma brucei</italic> , <italic>Leishmania major</italic> , and <italic>Plasmodium falciparum</italic> , and was identified to be a potent proliferation inhibitor.

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