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Screening strategies to identify new chemical diversity for drug development to treat kinetoplastid infections

28 Aug 2013

Abstract excerpt

The Drugs for Neglected Diseases initiative (DNDi) has defined and implemented an early discovery strategy over the last few years, in fitting with its virtual R&D business model. This strategy relies on a medium- to high-throughput phenotypic assay platform to expedite the screening of compound libraries accessed through its collaborations with partners from the pharmaceutical industry. We review the pragmatic...

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PMID: 23985066
DOI: 10.1017/s003118201300142x

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