Article
Stem cell programs are retained in human leukemic lymphoblasts.
Oncogene - 16 Apr 2015
Fan D, Zhou X, Li Z, Li Z-Q, Duan C, Liu T, Zhang F, Huang Y, Zhang Y, Gao F, Guo Y, Gupta R, Chen G, Enver T, Tang J, Hong D
Abstract excerpt
Leukemic lymphoblasts within different immunophenotypic populations possess stem cell properties. However, whether or not the self-renewal program is retained from stem cells or conferred on progenitors by leukemogenic molecules remains unknown. We have addressed the issue in the context of TEL-A...
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