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Article

RNA-seq analysis of virR and revR mutants of Clostridium perfringens.

BMC genomics - 23 May 2016

Low Lee-Yean, Harrison Paul F, Lin Ya-Hsun, Boyce John D, Rood Julian I, Cheung Jackie K

Abstract excerpt

BACKGROUND: Clostridium perfringens causes toxin-mediated diseases, including gas gangrene (clostridial myonecrosis) and food poisoning in humans. The production of the toxins implicated in gas gangrene, α-toxin and perfringolysin O, is regulated by the VirSR two-component regulatory system. In addition, RevR, an orphan response regulator, has been shown to affect virulence in the mouse myonecrosis model. RevR...

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Source

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Identifiers

PMID: 27216822
DOI: 10.1186/s12864-016-2706-2
PMCID: PMC4877802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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