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Article

A Long Journey before Cycling: Regulation of Quiescence Exit in Adult Muscle Satellite Cells

3 Feb 2022

Abstract excerpt

Skeletal muscle harbors a pool of stem cells called muscle satellite cells (MuSCs) that are mainly responsible for its robust regenerative capacities. Adult satellite cells are mitotically quiescent in uninjured muscles under homeostasis, but they exit quiescence upon injury to re-enter the cell cycle to proliferate. While most of the expanded satellites cells differentiate and fuse to form new myofibers, some...

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PMID: 35163665
DOI: 10.3390/ijms23031748

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