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Article

Key elements of the RNAi pathway are regulated by hepatitis B virus replication and HBx acts as a viral suppressor of RNA silencing.

The Biochemical journal - 1 Sept 2014

Chinnappan Mahendran, Singh Avishek Kumar, Kakumani Pavan Kumar, Kumar Gautam, Rooge Sheetalnath Babasaheb, Kumari Anupama, Varshney Aditi, Rastogi Archana, Singh Ashok Kumar, Sarin Shiv Kumar, Malhotra Pawan, Mukherjee Sunil Kumar, Bhatnagar Raj Kamal

Abstract excerpt

The host-mediated RNAi pathways restrict replication of viruses in plant, invertebrate and vertebrate systems. However, comparatively little is known about the interplay between RNAi and various viral infections in mammalian hosts. We show in the present study that the siRNA-mediated silencing of...

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Identifiers

PMID: 24902849
DOI: 10.1042/BJ20140316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24902849-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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