Article

Characterisation of palytoxin from an undescribed Palythoa (Anthozoa: Zoantharia: Sphenopidae) with significant in vitro cytotoxic effects on cancer cells at picomolar doses

2018-03-30

Abstract excerpt

Palytoxin (PlTX), a large polyhydroxylated compound, is among the most potent non-peptide toxin in marine organisms known so far. The literature emphasizes the sodium/potassium pump (NaK) as the privileged target for PlTX when exerting its toxic effects. In this study, we focused on an undescribed species ( Palythoa sp. Pc001), a coral species belonging to the genus Palythoa routinely cultivated in aquariums. We...

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Literature Corpus work: 2ea2d270-2bdb-556e-a3a0-78c54cf015bf
DOI: 10.1101/292219

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