Article
The significance of single nucleotide polymorphism rs2070770 in CD20 gene in Chinese patients with diffuse large B-cell lymphoma.
Leukemia & lymphoma - 1 Mar 2015
Zhang Li-Na, Wang Li, Fang Cheng, Zou Zhi-Jian, Fan Lei, Zhang Run, Young Ken H, Li Jian-Yong, Xu Wei
Abstract excerpt
The purpose of this study was to investigate the significance of polymorphisms in the CD20 gene in patients with diffuse large B-cell lymphoma (DLBCL). We sequenced exons 3-8 in 160 patients with de novo DLBCL and detected the expression of CD20 via immunohistochemistry. We found two single nucleotide polymorphisms (SNPs): rs17155019 in the 5' untranslated region and rs2070770 (ILE72/ILE72) in exon 4. There was...
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