Article
PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.
Epilepsy & behavior : E&B - 1 Jul 2014
Santos Bruna, Marques Thalita, Malta Maísa, Gameleira Fernando, Secolin Rodrigo, Andrade Tiago, Gitaí Lívia, Gitaí Daniel
Abstract excerpt
Sleep disturbance is common in several epilepsy types, such as juvenile myoclonic epilepsy (JME). Genetic background could increase susceptibility to seizure and sleep abnormalities. From this perspective, a susceptibility gene for sleep disturbance or chronotype could contribute to the genetic susceptibility threshold for epilepsy and vice versa. Accordingly, we investigated whether functional clock gene...
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