Phenotypic effects of genetic variability in human clock genes on circadian and sleep parameters.

doi:10.1007/s12041-008-0074-7

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Article

Phenotypic effects of genetic variability in human clock genes on circadian and sleep parameters.

Journal of genetics - 1 Dec 2008

von Schantz Malcolm

Abstract excerpt

Circadian rhythms and sleep are two separate but intimately related processes. Circadian rhythms are generated through the precisely controlled, cyclic expression of a number of genes designated clock genes. Genetic variability in these genes has been associated with a number of phenotypic differ...

Topics

Biological Clocks
CLOCK Proteins
Circadian Rhythm
Conserved Sequence
Genetic Variation
Humans
Phenotype
Protein Kinases
Sleep
Sleep Disorders, Circadian Rhythm
Trans-Activators
Transcription Factors

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