Article
Two novel, severe asthma phenotypes identified during childhood using a clustering approach.
The European respiratory journal - 1 Jul 2012
Just Jocelyne, Gouvis-Echraghi Rahele, Rouve Sarah, Wanin Stephanie, Moreau David, Annesi-Maesano Isabella
Abstract excerpt
Unsupervised cluster analysis has already been used to identify severe phenotypes of childhood asthma, but without taking into account inflammatory markers. The aim of this study was to define independent homogeneous phenotypic clusters of severe asthma in a cohort of asthmatic children. Cluster analysis was applied to 19 variables from 315 children enrolled in the Trousseau Asthma Program in Paris, France. Three...
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