Article
Genome-scale profiling reveals a subset of genes regulated by DNA methylation that program somatic T-cell phenotypes in humans.
Genes and immunity - 1 Jul 2012
Martino D, Maksimovic J, Joo J-He, Prescott S L, Saffery R
Abstract excerpt
The aim of this study was to investigate the dynamics and relationship between DNA methylation and gene expression during early T-cell development. Mononuclear cells were collected at birth and at 12 months from 60 infants and were either activated with anti-CD3 for 24 h or cultured in media alon...
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