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Article

BRCA2 promoter polymorphism is associated with breast cancer prognosis in Chinese women.

Chinese medical journal - 1 Jan 2014

Liu Lu, Fang Yi, Fan Jianlin, Hu Jianming, Xu Xiaoting, Jin Xiaohong, Wang Xiuzhen, Deng Min, Wang Jing, Liu Wei

Abstract excerpt

BACKGROUND: Breast cancer 2 (BRCA2) is an important breast cancer-susceptibility gene. Promoter polymorphisms in BRCA2 may affect its transcription and be associated with cancer prognosis. METHODS: We identified five polymorphisms of the BRCA2 promoter region by in silico searching and direct sequencing: -254A/G (rs3092989), -908A/G (rs206117), -1134A/G (rs206115), -1144C/T (rs206116), and -1260CTTAGA/-...

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PMID: 24890143

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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