Article
The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression.
PloS one - 1 Jan 2014
Boerkamp Kim M, van Steenbeek Frank G, Penning Louis C, Groot Koerkamp Marian J A, van Leenen Dik, Vos-Loohuis Manon, Grinwis Guy C M, Rutteman Gerard R
Abstract excerpt
Examination of gene functions in specific tumor types improves insight in tumorigenesis and helps design better treatments. Due to the rarity of histiocytic/dendritic cell sarcoma in humans, it is difficult to accrue such knowledge. Therefore, comparative research of these cancers in predisposed dog breeds, such as the Flatcoated retriever, can be of value. Histiocytic sarcoma in the dog can be grouped into a...
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