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Article

A novel flow cytometry-based cell capture platform for the detection, capture and molecular characterization of rare tumor cells in blood.

Journal of translational medicine - 23 May 2014

Watanabe Masaru, Serizawa Masakuni, Sawada Takeshi, Takeda Kazuo, Takahashi Toshiaki, Yamamoto Nobuyuki, Koizumi Fumiaki, Koh Yasuhiro

Abstract excerpt

BACKGROUND: Personalized cancer treatment relies on the accurate detection of actionable genomic aberrations in tumor cells. Circulating tumor cells (CTCs) could provide an alternative genetic resource for diagnosis; however, the technical difficulties in isolating and analyzing rare CTCs have limited progress to date. In this preclinical study, we aimed to develop an improved capture system for molecular...

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Topics

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Share to Antigens, Neoplasm
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cell Adhesion Molecule

Share to Flow Cytometry

Share to Genes, ras

Share to Immunomagnetic Separation

Share to Neoplastic Cells, Circulating

Share to Proto-Oncogene Proteins B-raf

Source

Open in PubMed Open full text

Identifiers

PMID: 24886394
DOI: 10.1186/1479-5876-12-143
PMCID: PMC4053587

Genes

EGFR
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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