Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Depigmented-polymerised allergoids favour regulatory over effector T cells: enhancement by 1α, 25-dihydroxyvitamin D3.

BMC immunology - 29 May 2014

Urry Zoe L, Richards David F, Black Cheryl, Morales Maria, Carnés Jerónimo, Hawrylowicz Catherine M, Robinson Douglas S

Abstract excerpt

BACKGROUND: Allergen immunotherapy (SIT) is the only treatment for allergic disease capable of modifying disease long term. To reduce the risk of anaphylaxis from SIT, allergen-extracts have been modified by polymerisation with glutaraldehyde to reduce IgE binding. It is suggested that these allergoid extracts also have reduced T cell activity, which could compromise clinical efficacy. Effective SIT is thought to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergens
Share to Calcitriol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypersensitivity

Share to Interleukin-2 Receptor alpha Subunit

Share to Interleukin-7 Receptor alpha Subunit

Share to Plant Extracts

Share to Poaceae

Share to Pyroglyphidae

Source

Open in PubMed Open full text

Identifiers

PMID: 24884430
DOI: 10.1186/1471-2172-15-21
PMCID: PMC4051145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Depigmented-polymerised allergoids favour regulatory over effector T cells: enhancement by 1α, 25-dihydroxyvitamin D3.PMID 24884430Read ↗

T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity.Semantic proximity Read ↗

Oral immunotherapy with omalizumab reverses the Th2 cell-like programme of regulatory T cells and restores their function.Semantic proximity Read ↗

Mechanisms of immunotherapy with allergoids: lessons for the development of recombinant allergens with reduced IgE-binding activity.Semantic proximity Read ↗

Methylation changes induced by a glycodendropeptide immunotherapy and associated to tolerance in miceSemantic proximity Read ↗

IL-10-modulated dendritic cells from birch pollen- and hazelnut-allergic patients facilitate Treg-mediated allergen-specific and cross-reactive toleranceSemantic proximity Read ↗

Flow cytometric analysis of cytokine expression in short-term allergen-stimulated T cells mirrors the phenotype of proliferating T cells in long-term cultures.Semantic proximity Read ↗

The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice.Semantic proximity Read ↗

Future advances of immunotherapy.Semantic proximity Read ↗

Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung.Semantic proximity Read ↗

From allergen structure to new forms of allergen-specific immunotherapySemantic proximity Read ↗

HLA class II peptide tetramers vs allergen-induced proliferation for identification of allergen-specific CD4 T cells.Semantic proximity Read ↗

Demonstration of circulating allergen-specific CD4+CD25highFoxp3+ T-regulatory cells in both nonatopic and atopic individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.